Melatonin

Melatonin [∞]

Melatonin

Alternate Names: N-Acetyl-5-Methoxytryptamine

Chart of Uses:

Use	Description	Index
Sleep Aid	Helps regulate the sleep-wake cycle, promoting restful sleep	{{ct:SleepAid}}
Jet Lag Management	Alleviates symptoms of jet lag by helping to adjust to new time zones	{{ct:JetLagManagement}}
Antioxidant Support	Acts as an antioxidant that helps protect cells from oxidative stress	{{ct:AntioxidantSupport}}
Mood Regulation	Supports mood stability by influencing serotonin and other neurotransmitters	{{ct:MoodRegulation}}
Immune System Support	May enhance immune function and reduce inflammation	{{ct:ImmuneSystemSupport}}

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Warnings:

1. Sleep Disruption: While melatonin helps with sleep, improper timing or high doses can disrupt sleep patterns.
2. Daytime Drowsiness: May cause drowsiness if taken during the day or if dosage is too high.
3. Pregnancy and Breastfeeding: Use only under medical supervision during pregnancy or breastfeeding.
4. Drug Interactions: May interact with blood thinners, immune-suppressing drugs, and medications for diabetes.
5. Blood Pressure: In some cases, melatonin can raise or lower blood pressure, so use cautiously in those with blood pressure issues.

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Active Compounds:

1. Melatonin: The primary active compound that regulates the body’s sleep-wake cycle and supports antioxidant and anti-inflammatory functions.
2. Serotonin: Melatonin is synthesized from serotonin, which plays a role in mood and sleep regulation.
3. N-Acetyltryptamine: Another form of melatonin that has similar effects in regulating biological rhythms.

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Natural Sources:

1. Fruits:
   • Cherries (Prunus avium): Particularly tart cherries are one of the best natural sources of melatonin.
   • Bananas (Musa spp.): Contains small amounts of melatonin and helps regulate sleep.
2. Vegetables:
   • Tomatoes (Solanum lycopersicum): Contain low amounts of melatonin, contributing to sleep regulation.
   • Corn (Zea mays): A plant-based source of melatonin, especially in dried corn.
3. Nuts and Seeds:
   • Walnuts (Juglans regia): A rich natural source of melatonin.
   • Flaxseeds (Linum usitatissimum): Contains trace amounts of melatonin, contributing to better sleep quality.
4. Herbs:
   • Tart cherry extract (Prunus cerasus): High in melatonin, often used as a supplement for sleep support.